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民国初年，吉祥镇九叔师徒行医济世，小镇接连出现命案，受害者在被咬伤后均死于某种疾病，九叔师徒开始了一场奇趣爆笑的追凶之旅，最终发现凶手是一些为了躲避灾祸藏于深山中被称为巫狼人的可怜人...。The Cold War has ended, and the Russian government has decided get rid of a deadly bioweapon sample by returning it to the United States, from whom it had been stolen. Officer Hendricks has been assigned to pick up the virus sample and escort it back to America via submarine. Along the way, however, a gang of terrorists hijack the sub in an attempt to launch a bioweapon attack ...。